Most new home based businesses will require certain start-up costs. These may include a new computer and computer desk, a printer, supplies, a fax machine, employee costs, consulting or accounting fees, a business phone, and printing costs for letterhead, envelopes, and business cards. With an online home business, you'll incur fees for new website design along with your domain name and hosting fees, promotion, and order processing expenses. These can add up in a hurry and are the main reason many new home based business owners don't make it.